SCHEMBL526059

SCHEMBL526059

NC(=S)Nc1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 5/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 1/20 0.62
TP53 P04637 1/20 0.60
TYR P14679 1/20 0.60
TSHR P16473 1/20 0.60
TAS2R38 P59533 1/20 0.60
HSD17B10 Q99714 1/20 0.60
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
HPGD P15428 1/20 0.59
ALOX12 P18054 1/20 0.59
CYP2C19 P33261 1/20 0.59
GAA P10253 2/20 0.55
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
EPHX1 P07099 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27517394 0.98 MAPT (0.61) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL6921083 0.88 ALDH1A1 (0.81) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL6982143 0.88 MAPT (0.52) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL725810 0.87 ALDH1A1 (0.75) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL9725073 0.84 ALDH1A1 (0.66) MAPTKDM4EALDH1A1NPC1RAB9A
Thiourea SCHEMBL1991944 0.84 MAPT (0.73) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL10189868 0.81 EPHX1 (0.60) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL5445907 0.80 MAPT (0.75) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL8956455 0.80 MAPT (0.75) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL4395392 0.80 MAPT (0.61) MAPTKDM4EALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462459-B Low-sensitization epoxy resin curing agent and preparation method thereof 安徽美东生物材料有限公司 2025-05-06 CN claimed
CN-119462459-A Low-sensitization epoxy resin curing agent and preparation method thereof 安徽美东生物材料有限公司 2025-02-18 CN claimed
CN-115532081-A Acid-resistant positive charge nanofiltration composite membrane and preparation method thereof 广东奥斯博膜材料技术有限公司 2022-12-30 CN claimed
CN-114432901-A Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-103373969-A Phenyl imidazole ring-substituted amide compounds as well as preparation method and application for same SHANGHAI INST ORGANIC CHEM 2013-10-30 CN claimed
CN-101687816-A Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases IPSEN PHARMA SAS 2010-03-31 CN claimed
US-4363913-A Preparation of 2-aminobenzothiazoles EASTMAN KODAK COMPANY (US) 1982-12-14 US claimed
EP-4629980-A1 ANTIMICROBIAL COMPOUNDS SRI International (US) 2025-10-15 EP disclosed
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-06-12 US disclosed
CN-119462459-B Low-sensitization epoxy resin curing agent and preparation method thereof 安徽美东生物材料有限公司 2025-05-06 CN disclosed
US-20250092020-A1 IDO/TDO Inhibitor GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) 2025-03-20 US disclosed
CN-119462459-A Low-sensitization epoxy resin curing agent and preparation method thereof 安徽美东生物材料有限公司 2025-02-18 CN disclosed
US-12209079-B2 IDO/TDO inhibitor GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) 2025-01-28 US disclosed
US-4657632-A CONTAINING A THIOUREA AND A UREA COMPOUND TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-04-14 US disclosed
EP-0216531-A1 Use of immersion tin and tin alloys as a bonding medium for multilayer circuits TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) 1987-04-01 EP disclosed
US-4563533-A FROM CORRESPONDING PHENYLTHIOUREAS HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
EP-0152021-A2 Phthalimide derivatives, their preparation and their use as agricultural fungicides SANKYO COMPANY LIMITED (JP) 1985-08-21 EP disclosed
US-4363913-A Preparation of 2-aminobenzothiazoles EASTMAN KODAK COMPANY (US) 1982-12-14 US disclosed
US-4148657-A WEAR RESISTANCE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-04-10 US disclosed
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12209079-B2 IDO/TDO inhibitor IDO1, IDO2, TDO2 MAPT 609/4885KDM4E 1315/4885ALDH1A1 3331/4885
US-20250092020-A1 IDO/TDO Inhibitor IDO1, IDO2, TDO2 MAPT 609/4885KDM4E 1315/4885ALDH1A1 3331/4885
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 MAPT 2614/4885KDM4E 1179/4885ALDH1A1 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.