Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.31 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24954134 | 0.81 | PARP1 (0.50) | KDM4EPARP1PARP3PARP15ACHE | |
| SCHEMBL9886276 | 0.72 | KDM4E (0.92) | KDM4EALDH1A1CYP1A2HPGDACHE | |
| SCHEMBL10663924 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2HPGDACHE | |
| SCHEMBL29941595 | 0.68 | PARP1 (0.41) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL14483361 | 0.67 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9583329 | 0.67 | ACHE (0.67) | KDM4EPARP1PARP3PARP15ALDH1A1 | |
| SCHEMBL9287302 | 0.66 | KDM4E (0.55) | KDM4EPARP1ALDH1A1CYP1A2HPGD | |
| SCHEMBL24954133 | 0.65 | PARP1 (0.39) | KDM4EPARP1PARP3PARP15TNKS | |
| SCHEMBL13494550 | 0.63 | KDM4E (0.52) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL13494563 | 0.63 | KDM4E (0.52) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |