Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752576 | 1.00 | CTSK (0.42) | CTSKMAPK1GPR88HPGDNOTUM | |
| SCHEMBL23752466 | 1.00 | CTSK (0.42) | CTSKMAPK1GPR88HPGDNOTUM | |
| SCHEMBL18010971 | 0.84 | CTSK (0.44) | CTSKMAPK1GPR88HPGDNOTUM | |
| SCHEMBL17351833 | 0.79 | CTSK (0.36) | CTSKMAPK1GPR88 | |
| SCHEMBL19859494 | 0.70 | LMNA (0.36) | MAPK1 | |
| SCHEMBL19859495 | 0.70 | LMNA (0.36) | MAPK1 | |
| SCHEMBL23092245 | 0.69 | FFAR1 (0.36) | CTSKGPR88HPGDNOTUM | |
| SCHEMBL19859532 | 0.69 | LMNA (0.36) | MAPK1 | |
| SCHEMBL19859533 | 0.69 | LMNA (0.36) | MAPK1 | |
| SCHEMBL19859672 | 0.69 | LMNA (0.36) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |