Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | MMP8 | P22894 | 6/20 | 0.49 |
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | MMP14 | P50281 | 6/20 | 0.49 |
| ▸ | MMP7 | P09237 | 5/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP3 | P08254 | 4/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353236 | 1.00 | MMP2 (0.49) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2354151 | 0.94 | ADAMTS4 (0.58) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2354755 | 0.91 | POLB (0.48) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2349607 | 0.89 | NPSR1 (0.52) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2352197 | 0.89 | ADAMTS4 (0.42) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2353443 | 0.89 | MMP2 (0.49) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2354741 | 0.88 | SLC1A3 (0.41) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL2353824 | 0.87 | SLC1A3 (0.43) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL23752492 | 0.87 | ANPEP (0.41) | MMP2MMP9MMP8MMP13MMP14 | |
| SCHEMBL23752491 | 0.87 | ANPEP (0.41) | MMP2MMP9MMP8MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |