Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 14/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430680 | 1.00 | KCNH2 (0.40) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL23753226 | 0.94 | KCNH2 (0.36) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL31430791 | 0.94 | KCNH2 (0.36) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL31430727 | 0.94 | KCNH2 (0.36) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL23753345 | 0.94 | KCNH2 (0.36) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL23753391 | 0.92 | CACNA1G (0.35) | KCNH2CACNA1G | |
| SCHEMBL31430721 | 0.92 | CACNA1G (0.35) | KCNH2CACNA1G | |
| SCHEMBL23753283 | 0.90 | ALDH1A1 (0.34) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL31430804 | 0.90 | ALDH1A1 (0.34) | KCNH2ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL23753242 | 0.87 | CACNA1G (0.34) | CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210255191-A1 | FLUORESCENT DYE AND USE THEREOF | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-08-19 | — | — | US | disclosed |
| US-20210255191-A1 | FLUORESCENT DYE AND USE THEREOF | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-08-19 | — | — | US | disclosed |