Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083707 | 0.90 | TDP1 (0.59) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL6282722 | 0.89 | ALDH1A1 (0.71) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL521687 | 0.87 | ALDH1A1 (0.69) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL27867043 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL6832765 | 0.84 | TDP1 (0.59) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL6833168 | 0.84 | TDP1 (0.64) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL29067021 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL6614027 | 0.83 | TDP1 (0.51) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL24874101 | 0.83 | TDP1 (0.51) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL26773019 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162493-A1 | PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2021-08-19 | — | — | WO | disclosed |
| WO-2021162493-A1 | PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2021-08-19 | — | — | WO | disclosed |