Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867043 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL6833168 | 0.87 | TDP1 (0.64) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL23754658 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL29388715 | 0.87 | ALDH1A1 (0.89) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL50441 | 0.87 | ALDH1A1 (0.89) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL18782372 | 0.86 | ALDH1A1 (0.64) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL27670732 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL26773019 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL4145578 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL15260788 | 0.84 | ALDH1A1 (0.77) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2021136805-A1 | NOVEL PqsR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2021-07-08 | — | — | WO | disclosed |
| EP-3798214-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2021-03-31 | — | — | EP | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |
| CN-102365255-B | Method for producing alcohol compound and catalyst therefor | SUMITOMO CHEMICAL CO | 2015-01-07 | — | — | CN | disclosed |
| CN-102365254-B | Method for producing alcohol compound | SUMITOMO CHEMICAL CO | 2014-08-27 | — | — | CN | disclosed |
| CN-102365255-A | Method for producing alcohol compound and catalyst therefor | SUMITOMO CHEMICAL CO | 2012-02-29 | — | — | CN | disclosed |
| CN-102365254-A | Method for producing alcohol compound | SUMITOMO CHEMICAL CO | 2012-02-29 | — | — | CN | disclosed |
| EP-2415741-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-02-26 | — | — | US | disclosed |
| CN-101336235-A | 1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as ptp-as inhibitors | NOVARTIS AG (CH) | 2008-12-31 | — | — | CN | disclosed |
| US-7312361-B2 | Inhibitors of transthyretin amyloid fibril formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1848688-A2 | INHIBITORS OF TRANSTHYRETIN AMYLOID FIBRIL FORMATION | The Scripps Research Institute (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006086517-A2 | INHIBITORS OF TRANSTHYRETIN AMYLOID FIBRIL FORMATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20060178527-A1 | Inhibitors of transthyretin amyloid fibril formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | TTR, TTPA, APOB | ALDH1A1 2778/4885TDP1 546/4885SLC6A2 1933/4885 |
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | ADH1A, ADH1C, ADH5 | ALDH1A1 18/4885TDP1 3832/4885SLC6A2 824/4885 |
| US-20120029195-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | ADH1A, ADH1C, ADH5 | ALDH1A1 33/4885TDP1 3331/4885SLC6A2 3005/4885 |
| US-20060178527-A1 | Inhibitors of transthyretin amyloid fibril formation | TTR, TTPA, APOB | ALDH1A1 2778/4885TDP1 546/4885SLC6A2 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.