SCHEMBL2375512

SCHEMBL2375512

C=CCc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.55
CA12 O43570 2/20 0.55
AKR1B10 O60218 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA3 P07451 2/20 0.55
AKR1B1 P15121 2/20 0.55
CA4 P22748 2/20 0.55
CA6 P23280 2/20 0.55
DPP4 P27487 2/20 0.55
CA5A P35218 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
ESR1 P03372 1/20 0.55
PKM P14618 1/20 0.55
TYR P14679 1/20 0.55
ESR2 Q92731 1/20 0.55
HDAC3 O15379 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3457764 0.85 HCAR2 (0.59) HCAR2CA12AKR1B10CA1CA2
SCHEMBL3457761 0.85 HCAR2 (0.59) HCAR2CA12AKR1B10CA1CA2
SCHEMBL5696000 0.84 GLA (0.53) AKR1B10AKR1B1ESR1HDAC3HDAC2
SCHEMBL10968639 0.81 ALDH1A1 (0.40) AKR1B1HDAC3HDAC1HDAC2HDAC8
SCHEMBL1363530 0.81 MAOB (0.47) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL5707226 0.81 KDM4E (0.56) HCAR2CA12AKR1B10CA1CA2
SCHEMBL8921111 0.80 TBXAS1 (0.68) HCAR2CA12AKR1B10CA1CA2
SCHEMBL713717 0.79 HCAR2 (0.81) HCAR2CA12AKR1B10CA1CA2
SCHEMBL68395 0.79 HCAR2 (0.81) HCAR2CA12AKR1B10CA1CA2
SCHEMBL14081549 0.79 HCAR2 (0.81) HCAR2CA12AKR1B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57104901-A None JP disclosed
EP-2367030-A2 Methacrylic resin composition for extruded light guide panel and light guide panel made thereof Sumitomo Chemical Company, Limited (JP) 2011-09-21 EP disclosed
EP-1165707-B1 PIGMENT PRINTING COMPOSITIONS AVECIA LTD (GB) 2004-11-17 EP disclosed
US-6794425-B1 Pigment printing composition AVECIA LIMITED (GB) 2004-09-21 US disclosed
US-6727296-B1 WATER-DISSIPATABLE POLYMER HAVING COLORANT ATTACHED; WATERPROOFING, LIGHTFASTNESS, AND OPTICAL DENSITY AVECIA LIMITED (GB) 2004-04-27 US disclosed
EP-1165707-A1 PIGMENT PRINTING COMPOSITIONS Avecia Limited (GB) 2002-01-02 EP disclosed
WO-2000052106-A1 PIGMENT PRINTING COMPOSITIONS AVECIA LIMITED (GB) 2000-09-08 WO disclosed
WO-2000037575-A1 INK-JET INK COMPOSITIONS AVECIA LIMITED (GB) 2000-06-29 WO disclosed
EP-0157481-B1 ORGANOSILOXANES AND PREPARATION THEREOF Dow Corning Limited (GB) 1990-09-12 EP disclosed
JP-S57104901-A SYNTHETIC RESIN LENS SEIKO EPSON CORP 1982-06-30 JP disclosed