Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846026 | 0.96 | AXL (0.92) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL27995075 | 0.87 | AXL (0.77) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL5566954 | 0.82 | AXL (0.69) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL2798028 | 0.82 | SMN1; SMN2 (1.00) | AXLSMN1; SMN2PDE3BPDE3AGPR119 | |
| SCHEMBL13335345 | 0.80 | AXL (0.67) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL5561143 | 0.80 | AXL (0.67) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL5561070 | 0.80 | AXL (0.67) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL20279531 | 0.80 | AXL (0.67) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL5566548 | 0.80 | AXL (0.66) | AXLSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL12402426 | 0.80 | AXL (0.66) | AXLSMN1; SMN2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 888 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036739-A | 3,4' -Pyrano [2,3-c ] pyrazole spiro oxindole derivative, and preparation method and application thereof | 遵义医药高等专科学校 | 2026-05-15 | — | — | CN | claimed |
| CN-122036691-A | 3-Phenyl-1H-pyrazol-5-alcohol spliced indole derivatives, and preparation method and application thereof | 遵义医药高等专科学校 | 2026-05-15 | — | — | CN | claimed |
| CN-118056816-A | Pyrazole-3-ketone derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-05-21 | — | — | CN | claimed |
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | claimed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | claimed |
| CN-1330637-A | Compounds useful in treatment of infammatory diseases | GLAXO GROUP LTD (GB) | 2002-01-09 | — | — | CN | claimed |
| EP-1140837-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037444-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2000-06-29 | — | — | WO | claimed |
| EP-0007019-A1 | 5-Phenyl-pyrazole derivatives and their salts, processes for their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1980-01-23 | — | — | EP | claimed |
| US-6423486-B1 | — | — | None | — | — | US | disclosed |
| CN-122036691-A | 3-Phenyl-1H-pyrazol-5-alcohol spliced indole derivatives, and preparation method and application thereof | 遵义医药高等专科学校 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036739-A | 3,4' -Pyrano [2,3-c ] pyrazole spiro oxindole derivative, and preparation method and application thereof | 遵义医药高等专科学校 | 2026-05-15 | — | — | CN | disclosed |
| US-20260042902-A1 | RUBBER COMPOSITION AND POWER STEERING HOSE | YOKOHAMA RUBBER CO LTD (JP) | 2026-02-12 | — | — | US | disclosed |
| US-20240208964-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | YUMANITY THERAPEUTICS, INC. | 2024-06-27 | — | — | US | disclosed |
| US-4923792-A | BENZYLIDENE LEUCO COMPOUNDS AS COLOR-GENERATING REDUCING AGENTS, TOPCOAT OF POLYVINYL ALCOHOL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4883747-A | LIGHT SENSITIVE SILVER HALIDE, ORGANIC ACID SILVER SALT, LEUCO DYE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0294099-A2 | Colour photothermographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |
| EP-0007019-A1 | 5-Phenyl-pyrazole derivatives and their salts, processes for their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1980-01-23 | — | — | EP | disclosed |
| EP-0007019-A1 | 5-Phenyl-pyrazole derivatives and their salts, processes for their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208964-A1 | PYRIDOPYRIMIDINES AND METHODS OF THEIR USE | PNPO, DPYD, PYGB | AXL 4694/4885SMN1; SMN2 7/4885ALDH1A1 945/4885 |
| US-20260042902-A1 | RUBBER COMPOSITION AND POWER STEERING HOSE | HSPA4L, ROS1, HSPE1 | AXL 2221/4885SMN1; SMN2 1149/4885ALDH1A1 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.