Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 8/20 | 0.78 |
| ▸ | ANPEP | P15144 | 8/20 | 0.78 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529859 | 1.00 | LAP3 (0.78) | LAP3ANPEPERAP2ERAP1ALPI | |
| Hydrochloric Acid SCHEMBL8693019 | 0.98 | LAP3 (0.75) | LAP3ANPEPERAP2ERAP1ALPI | |
| Bromide SCHEMBL9004890 | 0.98 | LAP3 (0.75) | LAP3ANPEPERAP2ERAP1ALPI | |
| Hydrochloric Acid SCHEMBL8689730 | 0.98 | LAP3 (0.75) | LAP3ANPEPERAP2ERAP1ALPI | |
| SCHEMBL8740148 | 0.88 | LAP3 (1.00) | LAP3ANPEPERAP2ERAP1ALPI | |
| SCHEMBL2375608 | 0.88 | LAP3 (1.00) | LAP3ANPEPERAP2ERAP1ALPI | |
| Bromide SCHEMBL15397852 | 0.86 | LAP3 (0.96) | LAP3ANPEPERAP2ERAP1ALPI | |
| L-Phenylalaninol SCHEMBL20271122 | 0.78 | LAP3 (0.63) | LAP3ANPEPERAP2ERAP1ALPI | |
| L-Phenylalaninol SCHEMBL28343751 | 0.78 | LAP3 (0.63) | LAP3ANPEPERAP2ERAP1ALPI | |
| Dextroamphetamine SCHEMBL547496 | 0.78 | TAAR1 (0.76) | LAP3ANPEPALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690066-B1 | Phosphinic acid derivatives, their preparation as well as their use | AVENTIS PHARMA GMBH (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0690066-A1 | Phosphinic acid derivatives, their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |