Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2375644 | 1.00 | ATM (0.68) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL3959739 | 1.00 | ATM (0.68) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| Hydrochloric Acid SCHEMBL17822192 | 0.98 | ATM (0.67) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| Hydrochloric Acid SCHEMBL1885087 | 0.98 | ATM (0.67) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| Hydrochloric Acid SCHEMBL1885086 | 0.98 | ATM (0.67) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL7260951 | 0.94 | ATM (0.62) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL2375126 | 0.93 | ATM (0.60) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL2375130 | 0.93 | ATM (0.60) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL5075625 | 0.91 | ATM (0.59) | ATML3MBTL1ALDH1A1THRBCYP2C9 | |
| SCHEMBL5887263 | 0.91 | ATM (0.59) | ATML3MBTL1ALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610081-B | Prepare method and the product of optical voidness N-methylamino acid esters | 浙江威拓精细化学工业有限公司 | 2016-09-07 | — | — | CN | disclosed |
| US-8552208-B2 | Analogs of tetramic acid | University of Tennesseee Research Foundation (US) | 2013-10-08 | — | — | US | disclosed |
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-15 | — | — | US | disclosed |
| EP-2185506-A1 | PYRROLE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST OR ANTAGONIST BIOLOGICAL ACTIVITY | Allergan, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009035553-A2 | ANALOGS OF TETRAMIC ACID | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20090069406-A1 | Analogs of tetramic acid | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-03-12 | — | — | US | disclosed |
| WO-2009026407-A1 | PYRROLE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST OR ANTAGONIST BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-0515548-A4 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-03-10 | — | — | EP | disclosed |
| US-5183810-A | Hyptoensive agents | MERCK & CO., INC. (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0515548-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012002-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO., INC. (US) | 1991-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | CTSA, BECN1, HDAC6 | ATM 4400/4885L3MBTL1 3413/4885ALDH1A1 3251/4885 |
| US-20090069406-A1 | Analogs of tetramic acid | TFRC, SLC7A1, FTH1 | ATM 4467/4885L3MBTL1 3347/4885ALDH1A1 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.