Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | BRD2 | P25440 | 2/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260736 | 0.82 | APLNR (0.39) | BRD4BRD2BRD3APLNRMAPK1 | |
| SCHEMBL14450662 | 0.82 | APLNR (0.39) | BRD4BRD2BRD3APLNRMAPK1 | |
| SCHEMBL4411373 | 0.79 | APLNR (0.42) | BRD4BRD2BRD3APLNRMAPK1 | |
| SCHEMBL19700360 | 0.78 | CA12 (0.46) | TSHRLMNASMN1; SMN2CA12CA1 | |
| SCHEMBL16230729 | 0.78 | CA12 (0.52) | TSHRLMNASMN1; SMN2CA12CA1 | |
| Hydrochloric Acid SCHEMBL26186841 | 0.78 | APLNR (0.41) | BRD4BRD2BRD3APLNRMAPK1 | |
| Hydrochloric Acid SCHEMBL26186849 | 0.78 | APLNR (0.41) | BRD4BRD2BRD3APLNRMAPK1 | |
| SCHEMBL13204637 | 0.77 | EPHX1 (0.39) | BRD4BRD2BRD3KCNH2TSHR | |
| SCHEMBL13958956 | 0.77 | CA1 (0.56) | MAPK1TSHRLMNASMN1; SMN2CA12 | |
| SCHEMBL12855687 | 0.77 | CA1 (0.56) | MAPK1TSHRLMNASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-01-20 | — | — | US | disclosed |
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | PIP4K2A, PIP5K1A, PIP4K2C | BRD4 265/4885BRD2 546/4885BRD3 432/4885 |
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | BRD4 276/4885BRD2 453/4885BRD3 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.