Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176218 | 1.00 | P2RX7 (0.47) | P2RX7GAAKMT2ACYP2C9CYP2C19 | |
| SCHEMBL21176335 | 0.88 | P2RX7 (0.48) | P2RX7GAAKMT2ACYP2C9CYP2C19 | |
| SCHEMBL21183582 | 0.85 | P2RX7 (0.51) | P2RX7GAAKMT2ACYP2C9CYP2C19 | |
| SCHEMBL21183578 | 0.85 | P2RX7 (0.51) | P2RX7GAAKMT2ACYP2C9CYP2C19 | |
| SCHEMBL19975341 | 0.84 | P2RX7 (0.46) | P2RX7GAAKMT2AALDH1A1CAPN1 | |
| SCHEMBL19974719 | 0.84 | P2RX7 (0.46) | P2RX7GAAKMT2AALDH1A1CAPN1 | |
| SCHEMBL21183603 | 0.84 | P2RX7 (0.52) | P2RX7GAAKMT2ACYP2C9CYP2C19 | |
| SCHEMBL21183549 | 0.83 | EPHX2 (0.50) | P2RX7GAAKMT2AALDH1A1CAPN1 | |
| SCHEMBL19974981 | 0.83 | P2RX7 (0.49) | P2RX7GAAKMT2ACAPN1ITGB1 | |
| SCHEMBL19974789 | 0.83 | P2RX7 (0.48) | P2RX7GAAKMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091428-B2 | Antiviral compounds | HAPLOGEN GMBH (AT) | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091428-B2 | Antiviral compounds | PLA2G1B, PLA2G12A, PLA2G4C | P2RX7 339/4885GAA 75/4885KMT2A 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.