Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760189 | 0.88 | ALDH1A1 (0.44) | MAPK1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23760128 | 0.86 | ALDH1A1 (0.42) | MAPK1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22035841 | 0.83 | KDM4E (0.38) | HTTMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL23760117 | 0.81 | IL1R1 (0.43) | HTTMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL23760181 | 0.80 | L3MBTL1 (0.36) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL22036681 | 0.79 | KDM4E (0.38) | HTTMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL19161309 | 0.78 | KDM4E (0.38) | HTTMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL20367811 | 0.77 | KDM4E (0.38) | HTTMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL19169959 | 0.77 | MAPK1 (0.47) | HTTMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL22425450 | 0.76 | ALDH1A1 (0.41) | HTTMAPK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |