Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15884097 | 0.83 | KDM4E (0.41) | KDM4ETSHRMCL1LMNAKMT2A | |
| SCHEMBL24571453 | 0.81 | KDM4E (0.40) | KDM4ETSHRMCL1LMNA | |
| SCHEMBL24180792 | 0.81 | KDM4E (0.40) | KDM4ETSHRMCL1LMNA | |
| SCHEMBL23760643 | 0.81 | KDM4E (0.40) | KDM4ETSHR | |
| SCHEMBL24571922 | 0.81 | KDM4E (0.40) | KDM4ETSHRLMNA | |
| SCHEMBL2622343 | 0.79 | TSHR (0.65) | KDM4ETSHRLMNA | |
| SCHEMBL819099 | 0.79 | TSHR (0.65) | KDM4ETSHRLMNA | |
| SCHEMBL1669126 | 0.79 | KDM4E (0.46) | KDM4ETSHRLMNA | |
| SCHEMBL24571482 | 0.78 | KDM4E (0.38) | KDM4ETSHR | |
| SCHEMBL12989964 | 0.76 | KDM4E (0.43) | KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019507-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | Philochem AG (CH) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021160825-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2021-08-19 | — | — | WO | disclosed |