Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622343 | 1.00 | TSHR (0.65) | TSHRKDM4ERECQLCPB1LDHA | |
| SCHEMBL18470361 | 0.85 | RECQL (0.48) | TSHRKDM4ERECQLCPB1LDHA | |
| SCHEMBL1669126 | 0.85 | KDM4E (0.46) | TSHRKDM4EGRIK1GRIK2KDM6B | |
| Aconitic Acid SCHEMBL31252804 | 0.83 | KDM4E (0.86) | TSHRKDM4ERECQLCPB1LDHA | |
| Aconitic Acid SCHEMBL30275008 | 0.82 | TSHR (0.95) | TSHRKDM4ERECQLCPB1LDHA | |
| Aconitic Acid SCHEMBL27922922 | 0.82 | TSHR (0.95) | TSHRKDM4ERECQLCPB1LDHA | |
| SCHEMBL12576175 | 0.81 | KDM4E (0.43) | TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL12989964 | 0.81 | KDM4E (0.43) | TSHRKDM4ECPB1ALOX15GRIK1 | |
| SCHEMBL23760642 | 0.79 | KDM4E (0.41) | TSHRKDM4ELMNA | |
| Aconitic Acid SCHEMBL27092737 | 0.79 | TSHR (0.78) | TSHRKDM4ERECQLCPB1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757407-B2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160346309-A1 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | UNIV PRINCETON (US) | 2016-12-01 | — | — | US | disclosed |
| US-9176381-B2 | Positive type photosensitive resin composition | CHEIL INDUSTRIES INC. (KR) | 2015-11-03 | — | — | US | disclosed |
| US-9176381-B2 | Positive type photosensitive resin composition | CHEIL INDUSTRIES INC. (KR) | 2015-11-03 | — | — | US | disclosed |
| US-9029413-B2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130065850-A1 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-03-14 | — | — | US | disclosed |
| US-8158677-B2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110159428-A1 | Positive Type Photosensitive Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2011-06-30 | — | — | US | disclosed |
| US-20110159428-A1 | Positive Type Photosensitive Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2011-06-30 | — | — | US | disclosed |
| EP-2292695-A1 | Positive type photosensitive composition | Korea Kumho Petrochemical Co. Ltd. (KR) | 2011-03-09 | — | — | EP | disclosed |
| US-20110053081-A1 | Positive Type Photosensitive Composition | KOREA KUMHO PETROCHEMICAL CO., LTD (KR) | 2011-03-03 | — | — | US | disclosed |
| US-20110053081-A1 | Positive Type Photosensitive Composition | KOREA KUMHO PETROCHEMICAL CO., LTD (KR) | 2011-03-03 | — | — | US | disclosed |
| US-20110053080-A1 | Positive Typed Photosensitive Composition | KOREA KUMHO PETROCHEMICAL CO., LTD (KR) | 2011-03-03 | — | — | US | disclosed |
| US-20110053080-A1 | Positive Typed Photosensitive Composition | KOREA KUMHO PETROCHEMICAL CO., LTD (KR) | 2011-03-03 | — | — | US | disclosed |
| EP-2290005-A1 | Positive type photosensitive composition | Korea Kumho Petrochemical Co. Ltd. (KR) | 2011-03-02 | — | — | EP | disclosed |
| US-20100047539-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN AND SEMICONDUCTOR DEVICE | KOREA KUMHO PETROCHEMICAL CO., LTD. | 2010-02-25 | — | — | US | disclosed |
| US-20100047539-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN AND SEMICONDUCTOR DEVICE | KOREA KUMHO PETROCHEMICAL CO., LTD. | 2010-02-25 | — | — | US | disclosed |
| US-20090239830-A1 | Treatment of viral infections by modulation of host cell metabolic pathways | KADMON CORPORATION, LLC | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239830-A1 | Treatment of viral infections by modulation of host cell metabolic pathways | GOT2, MAVS, ME3 | TSHR 4401/4885KDM4E 2299/4885RECQL 1986/4885 |
| US-20160346309-A1 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | GOT2, MAVS, ME3 | TSHR 4401/4885KDM4E 2299/4885RECQL 1986/4885 |
| US-20130065850-A1 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | GOT2, MAVS, ME3 | TSHR 4401/4885KDM4E 2299/4885RECQL 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.