Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.33 |
| ▸ | NPY4R | P50391 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25100586 | 0.87 | C3AR1 (0.42) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL24141108 | 0.87 | C3AR1 (0.42) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL17683438 | 0.84 | C3AR1 (0.42) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL27313920 | 0.84 | C3AR1 (0.41) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL18556667 | 0.84 | C3AR1 (0.41) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL17117124 | 0.83 | NMT2 (0.40) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL19698084 | 0.82 | C3AR1 (0.39) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL24831973 | 0.81 | ITGB3 (0.43) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL21481051 | 0.80 | ITGB3 (0.42) | C3AR1ITGB3ITGA2BTP53SMN1; SMN2 | |
| SCHEMBL20997125 | 0.80 | NPY4R (0.41) | NPY1RNPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160825-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2021-08-19 | — | — | WO | disclosed |