Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 2/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.48 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.48 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.47 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.46 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24081967 | 0.94 | P2RX1 (0.49) | TRPM2P2RX1P2RX3P2RX2PARG | |
| SCHEMBL24081955 | 0.84 | P2RX3 (0.51) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL23761014 | 0.82 | P2RY1 (0.42) | P2RX1P2RX3P2RX2P2RY1P2RY2 | |
| SCHEMBL20879494 | 0.81 | P2RX3 (0.55) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL23761036 | 0.81 | P2RX3 (0.49) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL21257339 | 0.81 | P2RX3 (0.53) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL24082005 | 0.80 | P2RX3 (0.51) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL18840499 | 0.78 | P2RX3 (0.57) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL22887211 | 0.77 | P2RX3 (0.55) | TRPM2P2RX1P2RX3P2RX2P2RY1 | |
| SCHEMBL21029886 | 0.76 | POLB (0.61) | TRPM2P2RX1P2RX3P2RX2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |