Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | IGF2R | P11717 | 4/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760811 | 1.00 | FBP1 (0.43) | FBP1AMDHD2TK1ENPP2LPAR2 | |
| SCHEMBL22268733 | 1.00 | FBP1 (0.43) | FBP1AMDHD2TK1ENPP2LPAR2 | |
| SCHEMBL24081814 | 0.87 | BTN3A1 (0.37) | — | |
| SCHEMBL23760746 | 0.87 | BTN3A1 (0.37) | — | |
| SCHEMBL19777920 | 0.87 | BTN3A1 (0.37) | — | |
| SCHEMBL22213532 | 0.86 | FBP1 (0.47) | FBP1AMDHD2IGF2R | |
| SCHEMBL22352074 | 0.86 | FBP1 (0.47) | FBP1AMDHD2IGF2R | |
| SCHEMBL18868813 | 0.86 | FBP1 (0.47) | FBP1AMDHD2IGF2R | |
| SCHEMBL23760848 | 0.84 | POLB (0.38) | — | |
| SCHEMBL23760859 | 0.84 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |