Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CDC20 | Q12834 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22889219 | 0.89 | ADORA3 (0.42) | ADORA3ADORA1ADORA2BCDK1PRKACA | |
| SCHEMBL24082139 | 0.87 | NR1I2 (0.46) | ADORA3ADORA1ADORA2BCDK1PRKACA | |
| SCHEMBL18831799 | 0.85 | HSP90AB1 (0.40) | — | |
| SCHEMBL23761068 | 0.79 | CCNE2 (0.39) | CDK1CDK2 | |
| SCHEMBL22580302 | 0.77 | ADORA3 (0.39) | ADORA3ADORA1ADORA2BCDK1PRKACA | |
| SCHEMBL20052484 | 0.77 | PI4KA (0.52) | ADORA1ADORA2BADORA2A | |
| SCHEMBL22224567 | 0.76 | CDK2 (0.44) | ADORA3ADORA1ADORA2BCDK1PRKACA | |
| SCHEMBL22580897 | 0.75 | CDK1 (0.43) | ADORA2BCDK1CDK2ADORA2A | |
| SCHEMBL26039600 | 0.74 | ADORA3 (0.36) | ADORA3ADORA1ADORA2BCDK1PRKACA | |
| SCHEMBL19644788 | 0.72 | PDE4A (0.32) | CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865136-A1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR CORONA VIRUS TREATMENT | ATEA Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |