Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23761010 | 0.87 | ADORA3 (0.43) | ADORA3ADORA1ADORA2AADORA2BCDK2 | |
| SCHEMBL18831799 | 0.81 | HSP90AB1 (0.40) | — | |
| SCHEMBL23761068 | 0.80 | CCNE2 (0.39) | CDK2CDK1 | |
| SCHEMBL11303595 | 0.77 | NR1I2 (0.51) | NR1I2ALBPDE4DPOLBABCB1 | |
| SCHEMBL22889219 | 0.77 | ADORA3 (0.42) | PDE4DADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL26795536 | 0.75 | NR1I2 (0.50) | NR1I2ALBPDE4DPOLBABCB1 | |
| SCHEMBL19050108 | 0.74 | TP53 (0.38) | POLB | |
| SCHEMBL20052484 | 0.73 | PI4KA (0.52) | ADORA1ADORA2AADORA2B | |
| SCHEMBL24939936 | 0.73 | CDK2 (0.49) | NR1I2ALBPDE4DPOLBABCB1 | |
| SCHEMBL22224963 | 0.72 | CDK2 (0.48) | NR1I2ALBPDE4DPOLBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |