Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759603 | 0.90 | BLM (0.48) | BLMLMNAPTPN1PTPN2CDC25B | |
| SCHEMBL4714067 | 0.90 | BLM (0.48) | BLMLMNAPTPN1PTPN2CDC25B | |
| SCHEMBL3780110 | 0.88 | BLM (0.50) | BLMLMNAPTPN1PTPN2CDC25B | |
| SCHEMBL15028271 | 0.87 | LMNA (0.48) | BLMLMNAPTPN1PTPN2CDC25B | |
| SCHEMBL26187571 | 0.86 | BLM (0.48) | BLMLMNAPTPN1PTPN2CDC25B | |
| SCHEMBL6024565 | 0.85 | BLM (0.44) | BLMLMNAPTPN1ALDH1A1 | |
| SCHEMBL26022016 | 0.84 | PTPN1 (0.35) | BLMPTPN1PTPN2CDC25B | |
| SCHEMBL22151947 | 0.83 | BLM (0.37) | BLMLMNAPTPN1PTPN2CDC25B | |
| SCHEMBL9935621 | 0.81 | MMP1 (0.38) | ALDH1A1 | |
| SCHEMBL22823947 | 0.80 | BLM (0.33) | BLMLMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160766-A1 | LIPID COMPOSITION AND USE THEREOF FOR DELIVERY OF A THERAPEUTICALLY ACTIVE AGENT TO ENDOTHELIUM | PANTHERNA THERAPEUTICS GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |
| EP-3865122-A1 | LIPID COMPOSITION AND USE THEREOF FOR DELIVERY OF A THERAPEUTICALLY ACTIVE AGENT TO ENDOTHELIUM | Pantherna Therapeutics GmbH (DE) | 2021-08-18 | — | — | EP | disclosed |