Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469201 | 0.91 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1KDM4EAPOBEC3ARAB9A | |
| SCHEMBL9244066 | 0.87 | PDE5A (0.41) | SIGMAR1PDE5AALDH1A1KDM4EAPOBEC3A | |
| SCHEMBL8373962 | 0.86 | PDE5A (0.48) | SIGMAR1PDE5AALDH1A1 | |
| SCHEMBL7643574 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G | |
| Styrene SCHEMBL2380965 | 0.84 | ALDH1A1 (0.50) | SIGMAR1ALDH1A1HTR2AEGFRHDAC3 | |
| SCHEMBL6543156 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G | |
| Styrene SCHEMBL2261497 | 0.83 | ALDH1A1 (0.48) | SIGMAR1ALDH1A1HTR2AEGFRHDAC3 | |
| Butadiene SCHEMBL10611751 | 0.82 | SIGMAR1 (0.45) | SIGMAR1HTR2AEGFRHDAC3 | |
| SCHEMBL22082 | 0.82 | SIGMAR1 (0.50) | SIGMAR1HTR2AEGFRHDAC3 | |
| SCHEMBL1295478 | 0.82 | SIGMAR1 (0.50) | SIGMAR1HTR2AEGFRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988873-B1 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | LUBRIZOL ADVANCED MAT INC (US) | 2013-01-09 | — | — | EP | claimed |
| US-8021650-B2 | Polymers containing silicone copolyol macromers and personal care compositions containing same | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2011-09-20 | — | — | US | claimed |
| EP-1988873-A2 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | Lubrizol Advanced Materials, Inc. (US) | 2008-11-12 | — | — | EP | claimed |
| WO-2007101059-A2 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070202069-A1 | Polymers Containing Silicone Copolyol Macromers and Personal Care Compositions Containing Same | LUBRIZOL ADVANCED MATERIALS, INC. | 2007-08-30 | — | — | US | claimed |