Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL3586505 | 0.96 | TSHR (0.47) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL11578827 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL1938734 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL11578822 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL5961174 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL9551431 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL3160181 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL9551433 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL6806779 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL3160195 | 0.92 | LMNA (0.48) | LMNATSHRCA4CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732605-B1 | MULTI-VITAMIN AND MINERAL NUTRITIONAL SUPPLEMENTS | WYETH LLC (US) | 2019-05-08 | — | — | EP | disclosed |
| US-8927012-B2 | Multi-vitamin and mineral nutritional supplements | WYETH LLC (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140017312-A1 | Multi-vitamin and Mineral Nutritional Supplements | WYETH LLC (US) | 2014-01-16 | — | — | US | disclosed |
| US-20110223250-A1 | MULTI-VITAMIN AND MINERAL NUTRITIONAL SUPPLEMENTS | WYETH LLC (US) | 2011-09-15 | — | — | US | disclosed |
| EP-1732605-A4 | MULTI-VITAMIN AND MINERAL NUTRITIONAL SUPPLEMENTS | WYETH CORP (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1732605-A2 | MULTI-VITAMIN AND MINERAL NUTRITIONAL SUPPLEMENTS | Wyeth (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005094333-A2 | MULTI-VITAMIN AND MINERAL NUTRITIONAL SUPPLEMENTS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |
| US-20050214383-A1 | Multi-vitamin and mineral nutritional supplements | WYETH LLC | 2005-09-29 | — | — | US | disclosed |