Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452018 | 0.73 | TAAR1 (0.34) | — | |
| SCHEMBL23370334 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL8845065 | 0.73 | CYP2A6 (0.36) | TYMP | |
| SCHEMBL23183088 | 0.73 | CYP2A6 (0.36) | TYMP | |
| SCHEMBL8845067 | 0.73 | CYP2A6 (0.36) | TYMP | |
| SCHEMBL19121802 | 0.70 | TLR8 (0.33) | — | |
| SCHEMBL598503 | 0.69 | TDP2 (0.37) | — | |
| SCHEMBL31095112 | 0.69 | TDP2 (0.37) | — | |
| SCHEMBL28184235 | 0.68 | GABRA1 (0.41) | — | |
| SCHEMBL28418503 | 0.68 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464286-B1 | PYRAZOLOPYRIDINE DERIVATIVES FOR THE TREATMENT OF CANCER | GENENTECH INC (US) | 2021-08-18 | — | — | EP | disclosed |