Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 4/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763554 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL23763600 | 0.85 | PDE2A (0.33) | SMN1; SMN2ALDH1A1LMNAPDE2AADORA2A | |
| SCHEMBL23763576 | 0.83 | — | — | |
| SCHEMBL23763393 | 0.83 | MAPT (0.40) | ALDH1A1LMNAPDE2APDE10AKDM4E | |
| SCHEMBL23763499 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1LMNAPDE2AKDM4E | |
| SCHEMBL23763729 | 0.76 | — | — | |
| SCHEMBL23763632 | 0.76 | SRC (0.38) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL23763599 | 0.75 | — | — | |
| SCHEMBL23763743 | 0.75 | HTR1D (0.32) | — | |
| SCHEMBL23763633 | 0.75 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNAPDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |