Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763589 | 0.85 | SMN1; SMN2 (0.33) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL23763499 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL23763423 | 0.74 | CYP19A1 (0.34) | ALDH1A1MAPK1MAPTTP53ABCG2 | |
| SCHEMBL23763627 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL23763598 | 0.74 | LMNA (0.34) | ALDH1A1KDM4EMAPK1MAPTLMNA | |
| SCHEMBL23763425 | 0.74 | NR1H4 (0.38) | ALDH1A1MAPK1MAPTABCG2NPC1 | |
| SCHEMBL22062846 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL23763733 | 0.73 | PLK4 (0.36) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL22088726 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL23763539 | 0.71 | SMN1; SMN2 (0.35) | ALDH1A1KDM4EHPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |