SCHEMBL23764501

SCHEMBL23764501

Cc1ccccc1-c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
MCL1 Q07820 1/20 0.38
MAPT P10636 1/20 0.38
PABPC1 P11940 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTR7 P34969 3/20 0.37
ESR2 Q92731 1/20 0.35
TRPA1 O75762 1/20 0.35
CTSD P07339 1/20 0.35
BACE1 P56817 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
ENPP3 O14638 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764110 0.96 KDM4E (0.40) KDM4EMCL1MAPTPABPC1SMN1; SMN2
SCHEMBL23764464 0.90 MCL1 (0.35) KDM4EMCL1MAPTHTR7ESR2
SCHEMBL23764168 0.88 KDM4E (0.37) KDM4EMCL1MAPTPABPC1SMN1; SMN2
SCHEMBL9888959 0.88 CRHBP (0.42) KDM4EMCL1MAPTPABPC1SMN1; SMN2
SCHEMBL16485045 0.86 MAPT (0.36) KDM4EMCL1MAPTPABPC1SMN1; SMN2
SCHEMBL9888927 0.85 CRHBP (0.44) KDM4EMAPTPABPC1SMN1; SMN2ALDH1A1
SCHEMBL23764165 0.84 MAPT (0.38) KDM4EMAPTPABPC1SMN1; SMN2ALDH1A1
SCHEMBL23764362 0.84 HPRT1 (0.35) KDM4EMCL1MAPTPABPC1SMN1; SMN2
SCHEMBL19393444 0.83 MCL1 (0.45) MCL1HTR7TRPA1CTSDBACE1
SCHEMBL23546684 0.83 CRHBP (0.43) KDM4EMAPTPABPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed