SCHEMBL23764530

SCHEMBL23764530

CC1(C)C=CC=C(N(c2ccccc2)c2nc3ccccc3n2-c2ccccc2)C=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.40
HTT P42858 1/20 0.40
CYP1A2 P05177 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
PDE10A Q9Y233 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
GSR P00390 1/20 0.33
TSHR P16473 3/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
CHRM2 P08172 3/20 0.32
CHRM4 P08173 3/20 0.32
CHRM5 P08912 3/20 0.32
CHRM1 P11229 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16483967 0.78 MAPK1 (0.54) MAPK1HTTCYP1A2ESR1ESR2
SCHEMBL19443891 0.76 ALDH1A1 (0.31) CYP1A2ALDH1A1CYP3A4MAPTCYP2C9
SCHEMBL23764529 0.75 CYP1A2 (0.33) CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL23764524 0.75 KDM4E (0.33) HTTTSHRALDH1A1MAPTCHRM2
SCHEMBL25697577 0.73 MAPK1 (0.59) MAPK1HTTCYP1A2ESR1ESR2
SCHEMBL23764408 0.73 NCF1 (0.41) HTTCYP1A2
SCHEMBL23764235 0.70 NPC1 (0.41) CYP1A2ESR1ESR2ALDH1A1CYP3A4
SCHEMBL12048765 0.70 MAPK1 (0.56) MAPK1HTTCYP1A2ESR1ESR2
SCHEMBL23764419 0.70 KCNA5 (0.33)
SCHEMBL20629310 0.69 HTT (0.30) HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed