Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR2B | P41595 | 4/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | KHK | P50053 | 4/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | MAP3K12 | Q12852 | 8/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455410 | 0.91 | HTR2C (0.60) | HTR2CHTR2AHTR2BADRB1KHK | |
| SCHEMBL29906021 | 0.91 | HTR2C (0.60) | HTR2CHTR2AHTR2BADRB1KHK | |
| SCHEMBL12968840 | 0.81 | HTR2C (0.49) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL24942475 | 0.78 | DYRK1A (0.51) | DYRK1AMAP3K12 | |
| SCHEMBL24942471 | 0.78 | DYRK1A (0.51) | DYRK1AMAP3K12 | |
| SCHEMBL27717820 | 0.78 | DYRK1A (0.51) | DYRK1AMAP3K12 | |
| SCHEMBL18997805 | 0.77 | HTR2C (0.44) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL14923154 | 0.77 | ADRB1 (0.64) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL18997802 | 0.76 | HTR2C (0.45) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL13677241 | 0.75 | ADRB1 (0.55) | HTR2CHTR2AHTR2BADRB1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161023-A1 | COMPOUNDS USEFUL IN INHIBITING KETOHEXOKINASE AND METHODS OF MAKING AND USING THE SAME | INORBIT THERAPEUTICS AB (SE) | 2021-08-19 | — | — | WO | disclosed |