Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.60 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HTR2B | P41595 | 4/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.49 |
| ▸ | KHK | P50053 | 7/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29906021 | 1.00 | HTR2C (0.60) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL23764796 | 0.91 | HTR2C (0.54) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL12968840 | 0.83 | HTR2C (0.49) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL23593003 | 0.79 | KHK (0.52) | KHKPDE10ANR1H2NR1H3 | |
| SCHEMBL14923154 | 0.79 | ADRB1 (0.64) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL24942410 | 0.76 | MAP4K1 (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL24942411 | 0.76 | MAP4K1 (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL8354208 | 0.75 | ADRB1 (0.78) | HTR2CHTR2AHTR2BADRB1RBP4 | |
| SCHEMBL23754730 | 0.75 | KHK (0.43) | HTR2CHTR2AHTR2BKHKPDE10A | |
| SCHEMBL13677241 | 0.74 | ADRB1 (0.55) | HTR2CHTR2AHTR2BADRB1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |