SCHEMBL23765156

SCHEMBL23765156

Clc1ccc(-c2cccc(-c3ccc(-c4ccc5c(c4)sc4cccc(Br)c45)cc3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.38
LIMK1 P53667 3/20 0.37
CYP1A2 P05177 2/20 0.35
CNR1 P21554 3/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B1 P14061 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
PAK4 O96013 1/20 0.31
PRKX P51817 1/20 0.31
ALOX5 P09917 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764989 0.97 PGR (0.36) PGRLIMK1CYP1A2CNR1CYP1A1
SCHEMBL21622688 0.88 LIMK1 (0.40) LIMK1RAB9A
SCHEMBL20391686 0.85 KDM4E (0.40) PGRLIMK1CYP1A2CNR1CYP1A1
SCHEMBL15989801 0.85 KDM4E (0.40) LIMK1KDM4ENPC1RAB9A
SCHEMBL29533985 0.85 KDM4E (0.40) LIMK1KDM4ENPC1RAB9A
SCHEMBL23764952 0.82 CYP2A6 (0.38) LIMK1CYP1A1CYP1B1
SCHEMBL21742816 0.81 PDE3B (0.43) LIMK1KDM4EHSD17B1NPC1RAB9A
SCHEMBL24969282 0.80 CYP1A2 (0.43) PGRLIMK1CYP1A2CNR1CYP1A1
SCHEMBL23764996 0.79 LIMK1 (0.36) PGRLIMK1CYP1A2CNR1CYP1A1
SCHEMBL31541870 0.78 PGR (0.44) PGRLIMK1KDM4ETAAR1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162384-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-08-19 WO disclosed