SCHEMBL23764952

SCHEMBL23764952

Clc1ccccc1-c1ccc(-c2ccc3c(c2)sc2cccc(Br)c23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.38
MAOB P27338 2/20 0.33
TNKS2 Q9H2K2 1/20 0.33
PRSS12 P56730 1/20 0.33
SLC9A1 P19634 1/20 0.33
F9 P00740 1/20 0.32
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32
TYK2 P29597 1/20 0.32
JAK3 P52333 1/20 0.32
HSD11B1 P28845 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
USP7 Q93009 1/20 0.31
MAP3K8 P41279 1/20 0.31
MAP2K1 Q02750 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764989 0.85 PGR (0.36) ALDH1A1LIMK1CYP1A1CYP1B1
SCHEMBL21622688 0.84 LIMK1 (0.40) F9ALDH1A1MAPK1LIMK1
SCHEMBL23765156 0.82 PGR (0.38) LIMK1CYP1A1CYP1B1
SCHEMBL27282404 0.79 MCL1 (0.41) F9ALDH1A1MAPK1LIMK1
SCHEMBL24969156 0.79 MCL1 (0.41) F9ALDH1A1MAPK1LIMK1
SCHEMBL21742816 0.78 PDE3B (0.43) LIMK1
SCHEMBL25567689 0.78 CYP2A6 (0.42) CYP2A6TNKS2PRSS12SLC9A1F9
SCHEMBL24969282 0.77 CYP1A2 (0.43) F9ALDH1A1LIMK1CYP1A1CYP1B1
SCHEMBL24171878 0.76 MAPT (0.46) SLC9A1F9ALDH1A1MAPK1LIMK1
SCHEMBL29533985 0.75 KDM4E (0.40) MAOBSLC9A1ALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162384-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-08-19 WO disclosed