SCHEMBL237662

SCHEMBL237662

[c]1ccc(Sc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.50
MAOB P27338 3/20 0.50
HPGD P15428 4/20 0.43
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGLL Q99685 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 2/20 0.38
HTR2C P28335 2/20 0.38
HTR6 P50406 1/20 0.38
SLC6A4 P31645 1/20 0.38
MCL1 Q07820 2/20 0.36
CHRNA7 P36544 1/20 0.35
HTT P42858 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023998 0.97 MAOA (0.54) MAOAMAOBHPGDMAPTSMN1; SMN2
SCHEMBL1712836 0.88 NR1H2 (0.40) MAOAMAOBHPGDMAPK1NR1H2
SCHEMBL27607754 0.85 MAOA (0.43) MAOAMAOBHPGDMAPTMGLL
SCHEMBL28107025 0.85 MAOA (0.48) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27841257 0.85 MAOA (0.62) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL2473224 0.85 MAOA (0.62) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL452 0.82 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27611905 0.82 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL28332331 0.82 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27714827 0.82 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 734 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185278-A Photo-curing composition, 3D printing photo-curing composition and application thereof 常州强力电子新材料股份有限公司 2024-06-14 CN claimed
CN-118131566-A Colored photosensitive resin composition and preparation method and application thereof 阜阳欣奕华材料科技有限公司 2024-06-04 CN claimed
CN-110121796-B Organic electroluminescent element and novel compound 出光兴产株式会社 2021-10-01 CN claimed
CN-111454598-A Light-cured composition suitable for irradiation curing of near-infrared L ED light source and application thereof 湖北固润科技股份有限公司 2020-07-28 CN claimed
CN-110305525-A A kind of radiation curing gravure ink 常州格林感光新材料有限公司 2019-10-08 CN claimed
CN-109563103-A modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto 艾尼纳制药公司 2019-04-02 CN claimed
CN-105968365-B A kind of Phenylsulfanylphenyl silicone/nano titania composite seal and preparation method thereof 广东鼎立森新材料有限公司 2019-01-15 CN claimed
CN-108314912-A A kind of UVLED Photocurable compositions and its application in floor coatings 常州格林感光新材料有限公司 2018-07-24 CN claimed
CN-107493684-A Photocurable composition 三键有限公司 2017-12-19 CN claimed
CN-107325237-A A kind of Free radical-Cationic Hybrid photocuring system and its application 常州强力电子新材料股份有限公司 2017-11-07 CN claimed
EP-0780386-A1 Matrix metalloprotease inhibitors F. HOFFMANN-LA ROCHE AG (CH) 1997-06-25 EP claimed
EP-0555058-B1 (Oxo)sulfonium complex, polymerizable composition containing the complex, and method of polymerizing composition TOYO INK MFG CO (JP) 1997-05-07 EP claimed
EP-0669315-A1 Ortho substituted phenylacetic acid amides BASF AKTIENGESELLSCHAFT (DE) 1995-08-30 EP claimed
EP-0615163-A1 Onium salts and positive resist materials using the same Shin-Etsu Chemical Co., Ltd. (JP) 1994-09-14 EP claimed
EP-0589985-A1 2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1994-04-06 EP claimed
WO-1993000342-A1 2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-01-07 WO claimed
EP-0519449-A1 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1992-12-23 EP claimed
EP-0108037-B1 PROPIOPHENONE DERIVATIVES AS PHOTOINITIATORS IN THE PHOTOPOLYMERIZATION CIBA-GEIGY AG (CH) 1989-06-07 EP claimed
EP-0237916-A2 1,1-Disubstituted cyclopropane derivatives, processes for their preparation and their use as antimycotics or as intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-23 EP claimed
EP-0236913-A2 Aryl-azolylmethyl-benzocyclo-alkene derivatives, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-16 EP claimed