Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439873 | 0.86 | MAPT (0.89) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL2138422 | 0.84 | MAPT (0.92) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL518954 | 0.81 | MAPT (1.00) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL15756724 | 0.81 | MAPT (0.50) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Diketopiperazine SCHEMBL29279043 | 0.77 | MAPT (0.53) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL22044245 | 0.76 | MAPT (0.63) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL21120273 | 0.76 | MAPT (0.89) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Hydantoin SCHEMBL5442026 | 0.74 | TSHR (0.50) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Sulfuric Acid SCHEMBL6194221 | 0.73 | MAPT (0.83) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Oxalic Acid SCHEMBL8173155 | 0.73 | MAPT (0.83) | MAPTNPC1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925771-B1 | A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES | COUNCIL SCIENT IND RES (IN) | 2021-08-18 | — | — | EP | disclosed |