Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL7756713 | 0.84 | MAPT (0.52) | MAPTTSHRCYP2A6MAOBMAOA | |
| Hydantoin SCHEMBL5442026 | 0.79 | TSHR (0.50) | MAPTTSHRCYP2A6MAOBMAOA | |
| SCHEMBL8119999 | 0.77 | MAPT (0.70) | MAPTTSHRCYP2A6MAOBMAOA | |
| SCHEMBL2062062 | 0.77 | NPC1 (0.52) | MAPTTSHRCYP2A6MAOBCA12 | |
| SCHEMBL3057782 | 0.77 | TSHR (0.86) | MAPTTSHRCYP2A6MAOBMAOA | |
| SCHEMBL29354295 | 0.77 | — | — | |
| SCHEMBL9662 | 0.77 | — | — | |
| SCHEMBL451157 | 0.77 | TSHR (0.86) | MAPTTSHRCYP2A6MAOBMAOA | |
| SCHEMBL23766313 | 0.77 | MAPT (0.67) | MAPTTSHRCYP2A6MAOBMAOA | |
| SCHEMBL5193435 | 0.76 | ALOX15 (0.57) | MAPTCA12CA9NPC1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914240-B | Norbornenone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-110914240-A | Norbornene ketone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2020-03-24 | — | — | CN | disclosed |