Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900928 | 0.86 | SLC10A1 (0.77) | SLC10A1 | |
| SCHEMBL23766573 | 0.81 | SLC10A1 (0.59) | SLC10A1 | |
| SCHEMBL26211886 | 0.78 | SLC10A1 (0.59) | SLC10A1 | |
| SCHEMBL20252930 | 0.78 | SLC10A1 (0.65) | SLC10A1 | |
| SCHEMBL19900988 | 0.78 | SLC10A1 (0.76) | SLC10A1 | |
| SCHEMBL19901021 | 0.77 | SLC10A1 (0.77) | SLC10A1 | |
| SCHEMBL19920752 | 0.77 | SLC10A1 (0.78) | SLC10A1 | |
| SCHEMBL20252937 | 0.77 | SLC10A1 (0.67) | SLC10A1 | |
| SCHEMBL19900992 | 0.76 | SLC10A1 (0.76) | SLC10A1 | |
| SCHEMBL20252963 | 0.76 | SLC10A1 (0.72) | SLC10A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210251957-A1 | SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210251957-A1 | SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF | HMBS, DHFR, HCCS | SLC10A1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.