SCHEMBL23767360

SCHEMBL23767360

CCCCCN1CCC2(CC1)CCN(CCCCC)CC2

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.53
S1PR3 Q99500 2/20 0.53
S1PR5 Q9H228 2/20 0.53
GNAI3 P08754 6/20 0.52
GNAO1 P09471 6/20 0.52
GNAI1 P63096 6/20 0.52
DRD2 P14416 1/20 0.47
DRD3 P35462 1/20 0.47
S1PR4 O95977 1/20 0.47
SIGMAR1 Q99720 4/20 0.46
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23767362 0.89 S1PR1 (0.51) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL23135328 0.86 DRD2 (0.49) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL24970676 0.86 S1PR1 (0.46) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL19159433 0.85 OPRM1 (0.52) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL20153230 0.84 S1PR1 (0.49) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL22859605 0.84 S1PR1 (0.49) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL24179174 0.84 S1PR1 (0.51) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL23518625 0.84 CYP2D6 (0.50) S1PR1S1PR3S1PR5S1PR4CYP1A2
SCHEMBL25653951 0.83 S1PR1 (0.54) S1PR1S1PR3S1PR5GNAI3GNAO1
SCHEMBL23806516 0.82 S1PR1 (0.44) S1PR1S1PR3S1PR5GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159559-A1 COMPOUND FOR INHIBITING AND INDUCING DEGRADATION OF EGFR KINASE BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) 2023-05-25 US disclosed
WO-2021163339-A1 CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS GENEVANT SCIENCES GMBH (US) 2021-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159559-A1 COMPOUND FOR INHIBITING AND INDUCING DEGRADATION OF EGFR KINASE EGFR, ERBB2, ERBB3 S1PR1 4379/4885S1PR3 4482/4885S1PR5 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.