Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516406 | 0.97 | KCNH2 (0.54) | KCNH2DNM1PLA2G1BPLA2G2AKDM5A | |
| SCHEMBL10527070 | 0.94 | KCNH2 (0.53) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL11336824 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| Hydrochloric Acid SCHEMBL5439092 | 0.94 | DNM1 (0.52) | KCNH2DNM1PLA2G1BPLA2G2AKDM5A | |
| SCHEMBL9174252 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL25341537 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL8750284 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL9852686 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL4251988 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR | |
| SCHEMBL8957984 | 0.94 | KCNH2 (0.57) | KCNH2DNM1PLA2G1BPLA2G2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163339-A1 | CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS | GENEVANT SCIENCES GMBH (US) | 2021-08-19 | — | — | WO | disclosed |