⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26455678 | 0.84 | — | — | |
| SCHEMBL23757701 | 0.83 | LPAR3 (0.39) | — | |
| SCHEMBL23767758 | 0.82 | FAAH (0.41) | — | |
| SCHEMBL26455766 | 0.80 | — | — | |
| SCHEMBL2006120 | 0.80 | ADRB2 (0.31) | — | |
| SCHEMBL26455751 | 0.79 | — | — | |
| SCHEMBL26455771 | 0.79 | — | — | |
| SCHEMBL26455692 | 0.77 | FAAH (0.33) | — | |
| SCHEMBL17937706 | 0.75 | — | — | |
| SCHEMBL17937810 | 0.74 | ADRB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139594-A1 | CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS | GENEVANT SCIENCES GMBH (CH) | 2023-05-04 | — | — | US | disclosed |
| US-20230139594-A1 | CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS | GENEVANT SCIENCES GMBH (CH) | 2023-05-04 | — | — | US | disclosed |
| WO-2021163339-A1 | CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS | GENEVANT SCIENCES GMBH (US) | 2021-08-19 | — | — | WO | disclosed |