Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 6/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30124830 | 1.00 | KDM5A (0.46) | KDM5AKDM5BFFAR1PTGER1CYP1A2 | |
| SCHEMBL30080316 | 0.92 | KDM5A (0.43) | KDM5AKDM5BPTGER1CYP1A2CYP2C9 | |
| SCHEMBL23767891 | 0.92 | KDM5A (0.43) | KDM5AKDM5BPTGER1CYP1A2CYP2C9 | |
| SCHEMBL23767893 | 0.89 | KDM5A (0.41) | KDM5AKDM5BPTGER1CYP1A2CYP2C9 | |
| SCHEMBL25544407 | 0.88 | PTGDR2 (0.48) | KDM5AKDM5BFFAR1XDHFFAR4 | |
| SCHEMBL23767752 | 0.83 | PTGER1 (0.46) | FFAR1PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL30021781 | 0.83 | PTGER1 (0.46) | FFAR1PTGER1CYP1A2CYP2C9TBXA2R | |
| SCHEMBL30080246 | 0.77 | ALKBH1 (0.51) | PTGER1CYP1A2PTGS1PTGER3PTGER2 | |
| SCHEMBL23767729 | 0.77 | ALKBH1 (0.51) | PTGER1CYP1A2PTGS1PTGER3PTGER2 | |
| SCHEMBL29141562 | 0.77 | FFAR4 (0.43) | KDM5AKDM5BFFAR1PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-06-01 | — | — | US | disclosed |
| CN-115697999-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2021160127-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | KDM5A 3899/4885KDM5B 3787/4885FFAR1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.