Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM4B | O94953 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30124830 | 0.88 | KDM5A (0.46) | KDM5AKDM4CKDM5BKDM4AKDM2B | |
| SCHEMBL23767892 | 0.88 | KDM5A (0.46) | KDM5AKDM4CKDM5BKDM4AKDM2B | |
| SCHEMBL25544411 | 0.88 | KDM5A (0.46) | PTGDR2KDM5AKDM4CKDM5BKDM4E | |
| SCHEMBL30080316 | 0.79 | KDM5A (0.43) | KDM5AKDM5BFFAR4XDHMAPT | |
| SCHEMBL23767891 | 0.79 | KDM5A (0.43) | KDM5AKDM5BFFAR4XDHMAPT | |
| SCHEMBL23767893 | 0.79 | KDM5A (0.41) | KDM5AKDM5BXDHSMN1; SMN2NPC1 | |
| SCHEMBL23767729 | 0.77 | ALKBH1 (0.51) | XDHPTGER4PDE4BMEN1KMT2A | |
| SCHEMBL30080246 | 0.77 | ALKBH1 (0.51) | XDHPTGER4PDE4BMEN1KMT2A | |
| SCHEMBL25544419 | 0.75 | DHODH (0.42) | KDM5AKDM4CKDM5BKDM2BXDH | |
| SCHEMBL25544417 | 0.73 | XDH (0.37) | KDM5AKDM4CKDM5BKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | PTGDR2 505/4885KDM5A 3899/4885KDM4C 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.