Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470106 | 0.94 | ALDH1A1 (0.75) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL19783828 | 0.94 | ALDH1A1 (0.75) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL27886560 | 0.94 | ALDH1A1 (0.75) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL22670505 | 0.86 | ALDH1A1 (0.69) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL31216171 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL20440475 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL7885120 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL5354462 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL14938581 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL8746080 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HSP90AA1FAAHHRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253554-A1 | SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253554-A1 | SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS | TYK2, JAK3, JAK2 | ALDH1A1 4424/4885HSP90AA1 3683/4885FAAH 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.