Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769111 | 0.78 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL15712770 | 0.67 | SMN1; SMN2 (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27939752 | 0.66 | CA12 (0.44) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30248720 | 0.65 | MAPT (0.57) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL31490268 | 0.65 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL23769116 | 0.65 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL30895175 | 0.64 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDTP53 | |
| Hydrochloric Acid SCHEMBL28914138 | 0.64 | MAPT (0.41) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL28942970 | 0.63 | TSHR (0.49) | MAPTALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL30364596 | 0.63 | TSHR (0.49) | MAPTALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |