Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256250 | 1.00 | ELANE (0.41) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL25138410 | 0.83 | STING1 (0.48) | STING1CACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL23769104 | 0.83 | STING1 (0.48) | STING1CACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL23769102 | 0.82 | STING1 (0.50) | STING1HPGDCACNA1GCACNA1HCACNA1I | |
| SCHEMBL29256261 | 0.82 | STING1 (0.50) | STING1HPGDCACNA1GCACNA1HCACNA1I | |
| SCHEMBL23769096 | 0.79 | STING1 (0.49) | STING1GSK3BCACNA1GCACNA1HCACNA1I | |
| SCHEMBL23769101 | 0.79 | STING1 (0.49) | STING1GSK3BCACNA1GCACNA1HCACNA1I | |
| SCHEMBL21932185 | 0.77 | STING1 (0.61) | STING1CACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL30128427 | 0.77 | STING1 (0.61) | STING1CACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL28913960 | 0.76 | STING1 (0.40) | ELANEF2PLGCTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | disclosed |