Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23768867 | 0.80 | DPP4 (0.31) | DPP4DPP8DPP7 | |
| SCHEMBL23769248 | 0.80 | DPP4 (0.31) | DPP4DPP8DPP7 | |
| SCHEMBL23769276 | 0.80 | DPP4 (0.31) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL23754084 | 0.79 | DPP4 (0.31) | DPP4DPP8DPP7 | |
| SCHEMBL23754096 | 0.68 | KLKB1 (0.30) | — | |
| SCHEMBL23769612 | 0.68 | KLKB1 (0.30) | — | |
| SCHEMBL12256571 | 0.67 | PDK1 (0.34) | APOBEC3AAPOBEC3G | |
| SCHEMBL24249677 | 0.64 | NOS3 (0.31) | — | |
| SCHEMBL15268287 | 0.64 | CACNA2D1 (0.31) | APOBEC3AAPOBEC3G | |
| SCHEMBL12256562 | 0.63 | DRD4 (0.36) | APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |