Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23768933 | 0.91 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL23754058 | 0.87 | KLKB1 (0.49) | KLKB1GRM2 | |
| SCHEMBL30087407 | 0.87 | KLKB1 (0.49) | KLKB1GRM2 | |
| SCHEMBL23769210 | 0.87 | KLKB1 (0.38) | KLKB1GRM2 | |
| SCHEMBL23843106 | 0.87 | KLKB1 (0.41) | KLKB1GRM2 | |
| SCHEMBL23769307 | 0.85 | ALDH1A1 (0.44) | KLKB1 | |
| SCHEMBL23754102 | 0.84 | KLKB1 (0.47) | KLKB1GRM2 | |
| SCHEMBL23769323 | 0.84 | KLKB1 (0.47) | KLKB1GRM2 | |
| SCHEMBL31357788 | 0.84 | KLKB1 (0.47) | KLKB1GRM2 | |
| SCHEMBL23769409 | 0.81 | GRM2 (0.39) | KLKB1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |