Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769049 | 0.85 | P2RX4 (0.45) | P2RX4CDK8TDP1FPR2MAOA | |
| SCHEMBL29979030 | 0.85 | P2RX4 (0.45) | P2RX4CDK8TDP1FPR2MAOA | |
| SCHEMBL25138406 | 0.84 | ITGB3 (0.51) | CDK8TDP1ITGB3ITGA2B | |
| SCHEMBL23768828 | 0.78 | CFTR (0.41) | P2RX4CDK8TDP1FPR2MAOA | |
| SCHEMBL29979369 | 0.78 | CFTR (0.41) | P2RX4CDK8TDP1FPR2MAOA | |
| SCHEMBL23768829 | 0.71 | KDM4E (0.44) | NPC1RAB9AMAPTKDM4EITGB3 | |
| SCHEMBL754538 | 0.71 | NR3C2 (0.53) | GAAHPGD | |
| SCHEMBL29979318 | 0.70 | ITGB3 (0.51) | CDK8TDP1ITGB3ITGA2B | |
| SCHEMBL23769073 | 0.70 | ITGB3 (0.51) | CDK8TDP1ITGB3ITGA2B | |
| SCHEMBL23768991 | 0.69 | NPC1 (0.49) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |