Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630484 | 0.90 | KDM4E (0.38) | KDM4ETSHRMCL1MEN1KMT2A | |
| SCHEMBL11573468 | 0.90 | — | — | |
| SCHEMBL17327897 | 0.83 | HRH3 (0.36) | HRH3KDM4E | |
| SCHEMBL20796436 | 0.83 | KDM4E (0.35) | KDM4ETSHRMCL1MEN1KMT2A | |
| SCHEMBL13881902 | 0.81 | MC4R (0.36) | KDM4ETSHRMCL1MEN1KMT2A | |
| SCHEMBL28225794 | 0.80 | SLC6A3 (0.38) | — | |
| SCHEMBL8737404 | 0.80 | SLC6A3 (0.38) | — | |
| SCHEMBL302084 | 0.80 | SLC6A3 (0.38) | — | |
| SCHEMBL20072506 | 0.79 | KDM4E (0.33) | KDM4ETSHRMCL1MEN1KMT2A | |
| SCHEMBL19629041 | 0.79 | KDM4E (0.40) | KDM4ETSHRMCL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458590-B9 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-08-18 | — | — | EP | disclosed |