SCHEMBL23770491

SCHEMBL23770491

CC1(C)c2ccccc2-c2c(-c3nc(-c4ccc(-c5ccncc5)cc4)nc(-c4ccc(-c5cccc6c5sc5ccccc56)cc4)n3)cccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
BACE1 P56817 1/20 0.36
BACE2 Q9Y5Z0 1/20 0.36
PDE10A Q9Y233 2/20 0.34
PARP14 Q460N5 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
LATS1 O95835 1/20 0.30
LATS2 Q9NRM7 1/20 0.30
PRKCI P41743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23770422 0.95 ALOX5 (0.38) ALOX5BACE1BACE2PDE10APARP14
SCHEMBL24682156 0.94 ALOX5 (0.42) ALOX5PARP14MAPTPRKDC
SCHEMBL20465203 0.94 ALOX5 (0.43) ALOX5BACE1BACE2PARP14MAPT
SCHEMBL20465224 0.94 ALOX5 (0.43) ALOX5BACE1BACE2PARP14MAPT
SCHEMBL23770420 0.93 ALOX5 (0.41) ALOX5PARP14MAPTPRKDC
SCHEMBL23770403 0.93 ALOX5 (0.41) ALOX5PARP14MAPTPRKDC
SCHEMBL23770311 0.93 ALOX5 (0.41) ALOX5PARP14MAPTPRKDC
SCHEMBL24682155 0.93 ALOX5 (0.43) ALOX5BACE1BACE2PARP14MAPT
SCHEMBL23770304 0.92 ALOX5 (0.42) ALOX5PARP14MAPTPRKDC
SCHEMBL23770492 0.91 PDK2 (0.37) ALOX5PDE10AMAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123170-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-20 US disclosed
WO-2021162122-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123170-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND L1CAM, LEF1, CCNL2 ALOX5 1852/4885BACE1 2098/4885BACE2 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.